Late in 2025, we covered the development of an AI system called Evo that was trained on massive numbers of bacterial genomes. So many that, when prompted with sequences from a cluster of related genes ...
Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...
Biology textbooks explain that cells follow a universal rule when processing gene transcripts to make proteins. Non-coding snippets of RNA are bracketed by a guanine-thymine (GT) nucleotide sequence ...
In 2009, Jonathan Weissman was hunting for a new way to spy on what happens inside a cell. In particular, the molecular cell biologist wanted to know what proteins are produced at any given moment. So ...
Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) report that inactivating a certain protein-coding gene promotes liver tissue regeneration in mammals. "This ...
The Human Domainome 1—the largest library of human protein variants—reveals the cause of certain genetic disorders, paving the way for personalized medicines. “We measured every possible mutation in ...